Willis M. Wu, M.D.

Return To Care Team




  • Spending time with family
  • Exercise, including running, biking, swimming
  • Collegiate lacrosse
  • Golf


  • Fellowship, Interventional Cardiology, Cleveland Clinic, Cleveland, OH
  • Fellowship, Cardiovascular Medicine, Chief Fellow, Cleveland Clinic, Cleveland, OH
  • Chief Fellow, Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH


  • Residency: Internal Medicine, Chief Resident, University of North Carolina Hospitals, Chapel Hill, NC
  • Chief Resident, Internal Medicine, University of North Carolina Hospitals, Chapel Hill, NC


  • Medical Degree: University of Maryland School of Medicine, Baltimore, MD
  • Undergraduate Degree: Princeton University, Princeton, NJ


  • Internal Medicine 2007
  • Cardiovascular Medicine 2011
  • Interventional Cardiology 2012
  • Registered Physician in Vascular Interpretation 2013


  • Fellow of the American College of Cardiology
  • American Registry for Diagnostic Medical Sonography


  • Coronary Intervention (Complex angioplasty, atherectomy, and stenting techniques including intervention of chronic total occlusions)
  • Peripheral Vascular Intervention (Carotid angiography, upper and lower extremity angioplasty, atherectomy, and stenting, renal and mesenteric artery intervention)
  • Cardiac Structural Intervention (Transcatheter Aortic Valve Replacement, balloon aortic valvuloplasty, Atrial Septal Defect and Patent Foramen Ovale closure, paravalvular leak closure, mitral valve intervention)


Research Publications:

  • Wu W, Masri A, Popovic ZB, Smedira NG, Lytle BW, Marwick TH,
    Griffin BP, Desai MY. “Long-term survival of patients with radiation
    heart disease undergoing cardiac surgery: a cohort study.” Circulation.
    2013 Apr 9;127(14):1476-84.
  • Wu W, Lincoff AM. “Pharmacotherapy During Saphenous Vein Graft
    Intervention.” Intervent Cardiol Clin 2 2013: 273-282.
  • Khurana RK, Wu WM, “The Valsalva Maneuver: A Literature Review and
    Personal Observations”, Autonomic Review, 2001, Volume: 5, Pages: 61-70.

Book Chapters:

  • Wu W, Runge M. “Sudden Cardiac Death in Athletes.” In: Runge, Patterson,
    Stouffer editors. Netter’s Cardiology 2nd Edition. Philadelphia, PA: Saunders
    Elsevier 2010.
  • Wu W, Kapadia S. “Risk Stratification and Post-Myocardial Infarction Therapy”
    In: Griffin, Kapadia, Rimmerman editors. The Cleveland Clinic Cardiology
    Board Review 2nd Edition. Philadelphia, PA: Lippincott. 2013: 627-640.
  • Wu W, Menon V. “Post-Myocardial Infarction Risk Stratification and
    Management.” In: Griffin, editor. Manual of Cardiovascular Medicine 4th
    Edition. Philadelphia, PA: Lippincott. 2013: 86-96.
  • “The role of percutaneous mitral repair for high risk patients” in Percutaneous
    Mitral Leaflet Repair: MitraClip Therapy for Mitral Regurgitation. 2013.


  • Wu W, Smedira N, Hammer D, Marwick T, Lytle B, Griffin B, Desai M.
    “Long-term outcomes of patients with radiation heart disease undergoing cardiac
    surgery: Clinical and Echocardiographic predictors” Presented at ACC 2011.
  • Ko C, Kim S, Wu WM, Chua SC, Jr., Huang L-S, “A Quantitative Trait Locus
    (QTL) on Chromosome 5 is Associated with Plasma ApoB responsiveness to
    Fish Oil in Human ApoB Transgenic Mouse Strains”, Supplement to American
    Journal of Human Genetics, 2001, Volume: 69, Page 525.

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